The difference between odds ratio and risk ratio • ericminikel The other day I was emailing with a statistical genetics colleague about a rare SNP associated with a phenotype I stated that the minor allele frequency (MAF) was 07% in cases and 01% in controls, for a risk ratio of 7 After clicking send, I felt a twinge of regret On the use, misuse and interpretation of odds ratios Dear Sir, In a recent article, Davies et al (1) commented on a potential problem when interpreting odds ratios (OR) as relative risks (RR) in epidemiological studies However, their vague concept of effect measures as applied to different study designs in epidemiology may lead to misuse and Odds ratios (OR) significantly overestimate associations between risk factors and common outcomes The estimation of relative risks (RR) or prevalence ratios (PR) has represented a statistical challenge in multivariate analysis and, furthermore, some researchers do not have access to the available methods Objective To propose and evaluate a new method for
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